Tissue Plasminogen Activator in a Vertebral Artery Dissection

Extension of "roller coaster dissection" after tissue plasminogen activator.

Plasminogen Activator A 40-year-old woman developed a right supraorbital headache after a series of roller coaster rides in a theme park. The headache fluctuated in intensity and was relieved with over-the-counter analgesics. One week later, she developed a sudden-onset left hemiparesis. She was taken to a local hospital, where a head CT finding was normal. CT angiography findings were consiste...

Optimizing refolding condition for recombinant tissue plasminogen activator

Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...

Extracranial vertebral artery dissection

Vertebral artery dissection (VAD) is not uncommon in the young adult population. Owing to the various clinical manifestations; the diagnosis of VAD mainly depends on imaging examinations. Ultrasound has found an increasingly wide utilization in the diagnosis of VAD because of the continuous improvement in the resolution of ultrasonic instruments and accessibility.We retrospectively collected th...

Extracranial vertebral artery dissection.

Vertebral Artery Dissection

Background and Purpose: In this study we analyzed the value of ultrasound examination for diagnosis of vertebral artery dissection. Methods: The vertebrobasilar arterial system was assessed in 14 patients using transcranial and extracranial pulsed-wave Doppler and duplex sonography. Results: The dissections were verified by angiography (in 1 patient), magnetic resonance imaging (in 5), or both ...